Straddling two time lines, The Resting Soul of Galileo follows the lives of two scientists and their daughters. In 1633, Galileo goes on trial for his heretical view that the Earth revolves around the Sun, while in 2019 Ammar Nouhan, a leading climatologist deals must defend his work against an administration who wants to silence any mention of climate change. Meanwhile, their daughters must find ways to pick up the pieces, keep their families united at all costs, and deal with their own questions of self-worth.