Stewart and Josie were friends in high school, where he was the gay guy and she was the fat girl. They made a pledge that if neither were married by the time they were 40, they would marry each other. Fast forward to today, when a chance meeting brings the two friends back together. Sharing tales of their crappy love lives, Stewart and Josie grow closer and closer until--could it be?--they fall in love, much to the dismay of Stweart's best friend Maxie, a "drag illusionist" best known for his caustic wit and love of making up dirty lyrics to show tunes, and to Lux, Josie's friend and roommate, a stage manager by trade who works part time at Josie's "maternity concierge" business, A Womb With a View. Can the former fat girl and current gay guy buck the odds and live happily ever after? Maybe the ghost of Marie Osmond can help!

Something is happening to the Earth. It's rotation is slowing down, so now nights last for 30 hours, sometimes more. The animals felt it first, the cats, the raccoons, then the humans. None of them know when to sleep. Satelites aren't working right, cell phone reception is spotty and the tides have gone awry and flooded all the coastal areas. Travis is almost 16. His dad left a few months back and his sister, KC, had to come home from her first year in college to take care of him after their mother stopped sleeping altogether and now stays up all night baking elaborate cakes and garbage bags full of cookies. Travis splits his free time between his girlfriend Marissa, and his older buddy, Merv, who manages the Chuck E. Cheese knock off in their town and who is always on the look out for "pervs". As Travis tries to manage in this ever changing world, KC is left to clean up her mom's messes. When her mom goes missing, KC checks with the neighbors and meets Mrs. Carlisle, a no-nonsense octogenarian widow, known as the the town's "crazy cat lady", who now sits in her wheelchair brandishing a shotgun. Just as an uneasy friendship is forming between the two women, something happens that sets in motion a chain reaction of events that will change everyone's lives forever.

Marko and Ness have returned to their Southern home for their father's funeral. Greeted by their father's common-law wife, Nomi, a trans woman who has been with their dad for decades. The stress of the situation brings out the worst in the siblings, who snipe and claw at each other, while slowly revealing to Nomi their own individual struggles with agoraphobia, eating disorders and abusive boyfriends. When their real mother announces she is coming to collect their father's ashes, Marko and Ness rally to support Nomi's rights to them, only to be shocked and horrified by what Nomi has done to keep the ashes where she thinks they should be.

Donnie, Richie and Dooch have been friends forever, growing up together in South Boston. Hanging out on a rooftop on night smoking a joint, their conversation turns to a topic near and dear to every Bostonians heart: baseball. Talking about their beloved Red Sox and other ball teams, this question gets posed: would you rather get to first base with Angelina Jolie or third base with Helen Hunt?

Connie, Margee and Heather have been best friends since they grew up together in South Boston. A girls' day at the local beach, replete with Heather's special "juice boxes" is something all of them need to get rid of the stress of their everyday lives. But when an unexpected phone call comes, these friends relize just how close they really are.

Dec and Mick are on a subway in Boston. Just a couple of dudes who have been friends since they were little. Dec's been having problems with his girlfriend and her obsession with the Twilight movies, which leads to the question: would you rather be a vampire or a werewolf? The conversation spins into other "sundry topics" and Mick, thinking he is in his own little world, breaks into a spirited lip-synch (and dance) to the song "If You Could Read My Mind". What Mick doesn't expect is that Dec can do just that.

Linda and Lisa were high school best friends from the North Shore of Boston who lost touch with each other, until one night in December when they run into each other at the mall. With accents as thick as chowdah, they catch up and relive good times, until a surprise threatens to blow up their friendship.

Find out what really happened with Herbie the Dentist that one Christmas...